At-Home NAD+ Injection Therapy in Fort Collins

What NAD+ Does

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of the body. It plays a central role in mitochondrial energy production, DNA repair, and the activity of sirtuins — a family of proteins associated with healthy aging. NAD+ is also a substrate for hundreds of enzymes involved in metabolic regulation.

NAD+ levels naturally decline with age. By midlife, many adults have substantially lower NAD+ than they did in their twenties. That decline is one of the mechanisms linked to age-related energy changes, reduced recovery capacity, and the gradual shifts in cellular function that come with getting older.

Supplementing NAD+ has been studied for its potential to support energy, sleep quality, cognitive function, and recovery. Individual response varies significantly, and outcomes depend on baseline NAD+ levels, lifestyle, and overall health.

Why Subcutaneous Home Injection (Not IV)

Most NAD+ therapy programs use intravenous infusion — patients sit in a clinic chair for 60 to 90 minutes per session, often weekly. At Peak Medical Wellness, we take a different approach: subcutaneous (SubQ) injection that patients self-administer at home, after a brief in-clinic training visit.

There are several reasons we prefer this delivery method:

• Convenience. A SubQ injection takes less than a minute. No clinic visits required after the initial training — patients dose at home on a schedule that works for them.
• Cost. SubQ NAD+ is meaningfully less expensive per dose than IV NAD+, which makes ongoing protocols more sustainable.
• Comfort. IV NAD+ is notoriously uncomfortable. Many patients describe cramping, chest tightness, anxiety, or flushing during infusion. SubQ injection avoids those reactions entirely.
• Steadier levels. Daily or every-other-day SubQ produces more consistent NAD+ levels than a weekly IV bolus, which spikes and then declines between sessions.
• Same physiological goal. For most patients seeking energy, recovery, and longevity support, SubQ NAD+ achieves the underlying benefit without the IV chair time.

IV NAD+ has a role in some specific clinical contexts (high-dose protocols, certain recovery medicine settings). For the wellness and longevity use cases most of our patients are interested in, SubQ is the better fit.

How the Program Works

NAD+ therapy at Peak Medical Wellness follows a clear, provider-led process:

• Consultation and intake. Your provider reviews your health history, current medications, goals, and any contraindications before prescribing.
• Personalized protocol. Dosing and frequency are tailored to your individual response and goals — there is no one-size-fits-all NAD+ dose.
• In-clinic training. You learn safe subcutaneous injection technique during a brief in-person visit. Most patients become comfortable in one session.
• At-home administration. You self-administer on the schedule your provider prescribes. Supplies are sent to your home.
• Follow-up and adjustment. A check-in at 4 to 8 weeks lets your provider assess response and adjust dose or frequency.

Who Is a Good Candidate?

NAD+ therapy tends to be most useful for:

• Adults in midlife and beyond noticing age-related energy or recovery changes
• Patients already in women's or men's hormone optimization who want to layer cellular energy support
• Patients on peptide therapy — NAD+ pairs naturally with growth-hormone-releasing peptides like sermorelin
• Adults interested in longevity strategies and healthy-aging support
• Patients focused on recovery from training, demanding work, or post-illness fatigue

NAD+ is generally not appropriate during pregnancy or breastfeeding, in patients with active malignancy, or in those with specific contraindications your provider will screen for at consultation.

What to Expect

Many patients notice subtle energy or focus changes within the first one to three weeks of consistent SubQ NAD+ injection. Recovery, sleep, and mood improvements often build more gradually over four to eight weeks. Some patients describe an immediate post-injection sense of clarity; others experience a slower, more cumulative shift in baseline. Individual response varies significantly.

The most common side effect is mild redness, warmth, or soreness at the injection site, similar to other subcutaneous medications. These reactions typically resolve within a day. Unlike IV NAD+, SubQ injection generally avoids the cramping, flushing, or chest discomfort some patients experience during infusion.

For the broader context on how NAD+ works mechanistically and how it compares to oral precursors like NR and NMN, see our complete NAD+ therapy guide.